New World Screwworm Approved Products
As of: May 1, 2026
The following information will be updated accordingly with new approvals from FDA and EPA. It is the intent of USAHA to provide up-to-date, accurate information. If you are aware of any updates needed, please submit those to brichey@usaha.org.
Animal Drugs Approved or Conditionally Approved by FDA for NWS
| Product | Approval or Conditional Approval? | Indication(s) | Species Freedom of Information | Summary |
|---|---|---|---|---|
| Dectomax-CA1 (doramectin injection) injectable solution | Conditional Approval | Prevention and treatment of infestations caused by larvae of Cochliomyia hominivorax (myiasis), and prevention of reinfestation for 21 days in cattle. | Cattle | cNADA 141-616 |
| Exzolt Cattle-CA1 (fluralaner) topical solution* | Conditional Approval | Prevention and treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) and treatment and control of cattle fever tick (Rhipicephalus microplus) in beef cattle 2 months of age and older and replacement dairy heifers less than 20 months of age. | Cattle | cNADA 141-617 |
| Credelio Quattro-CA1 (lotilaner, moxidectin, praziquantel, pyrantel) chewable tablets | Conditional Approval | Treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in dogs and puppies. | Dogs | cNADA 141-619 |
*extralabel use of this animal drug is not permitted
Emergency Use Authorizations Issued by FDA for NWS Animal Drugs
| Product | Indication(s) | Species | Links to additional information |
|---|---|---|---|
| Credelio (lotilaner) chewable tablets | Treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in dogs and puppies. | Dogs | FOI Summary Letter of Authorization Fact Sheet for Veterinarians Granting Letter |
| Credelio CAT (lotilaner) chewable tablets | Treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in cats and kittens. | Cats | FOI Summary Letter of Authorization Fact Sheet for Veterinarians |
| Ivomec (ivermectin) injectable solution | Prevention of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) when administered within 24 hours of birth, at the time of castration, or at the appearance of wound in cattle, except for female dairy cattle producing milk for human consumption and calves that will be processed for veal. | Cattle | FOI Summary Letter of Authorization Fact Sheet |
| NexGard (afoxolaner) chewable tablets | Treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in dogs and puppies. | Dogs | FOI Summary Letter of Authorization Fact Sheet for Veterinarians |
| NexGard COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) | Treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in cats and kittens. | Cats | FOI Summary Letter of Authorization Fact Sheet for Veterinarians |
| F10 Antiseptic Wound Spray with Insecticide (benzalkonium chloride, polyhexanide and cypermethrin topical solution)* | Prevention and treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in cattle, horses, minor species of hoof stock, raptors and other wild birds, pet birds, and captive wild, exotic, and zoo mammals. | Cattle Horses Minor Species of Hoof Stock Raptors, Wild Birds, Pet Birds Captive Wild, Exotic, and Zoo Mammals | FOI Summary Letter of Authorization Fact Sheet |
| F10 Antiseptic Barrier Ointment with Insecticide (benzalkonium chloride, polyhexanide and cypermethrin topical ointment)* | Prevention and treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in cattle, horses, minor species of hoof stock, raptors and other wild birds, pet birds, and captive wild, exotic, and zoo mammals. | Cattle Horses Minor Species of Hoof Stock Raptors, Wild Birds, Pet Birds Captive Wild, Exotic, and Zoo Mammals | FOI Summary Letter of Authorization Fact Sheet |
| Negasunt Powder (coumaphos, propoxur, and sulfanilamide topical powder)* | Prevention and treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in cattle, swine, goats, sheep, horses, donkeys, domestic hybrid equids, and captive wild, exotic, and zoo mammals. | Cattle Swine Goats Sheep Horses Donkeys Domestic hybrid equids Captive Wild, Exotic, and Zoo Mammals | FOI Summary Letter of Authorization Fact Sheet |
| Dectomax/Dectomax-CA1 (doramectin injection) | Prevention and treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in dairy cattle (lactating dairy cows, dry dairy cows, replacement dairy heifers, 20 months of age and older) except for calves that will be processed for veal; and Prevention of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in horses one year and older, swine, sheep except lactating sheep, and deer. | Dairy Cattle Horses Swine Sheep Deer | FOI Summary Letter of Authorization Fact Sheet – Dairy Cattle, Swine, Sheep, Deer Fact Sheet – Horses |
*extralabel use of this animal drug is not permitted
EPA Authorizations for NWS Products
| Product | Active Ingredient(s) | Prevention Prophylaxis Treatment C&D | Local / Systemic | Duration | Withholding for Meat; Milk | Regulatory Agency | Authorization | Species | Route of Administration |
|---|---|---|---|---|---|---|---|---|---|
| Catron IV | Permethrin | Prophylaxis Treatment | Local | Short | None | EPA | Registered | Cattle, sheep, goats, hogs, horses | Spray |
| Co-Ral Fly & Tick Spray | Coumaphos | Prevention – Fly Control | Local | Long | Meat 0 dys; Milk 14 dys | EPA | 2ee, Florida | Cattle | Spray Back Rubber |
| Elector PSP | Spinosad | C&D | Premises | Long | N/A – Premise | EPA | 2ee, Texas | Farm Animal | Spray |
| Cylence Ultra Premise | Beta-cyfluthrin | C&D | Premises | Long | N/A – Premise | EPA | 2ee, Texas | Farm Animal | Spray |
| Vapona | Dichlorvos | C&D | Premises | Long | N/A – Premise | EPA | 2ee, Texas | Farm Animal | Spray / Fog |
| Permectrin Fly & Louse Dust | Permethrin | Prevention – Fly Control* | Local | Long | None | EPA | 2ee, Florida, Alabama, Mississippi | Cattle, sheep, horses | Dust |
| Permectrin CDS | Permethrin | Prevention – Fly Control* | Local | Long | None | EPA | 2ee, Florida, Alabama, Mississippi | Cattle, sheep, horses | Spray, Pour-On, Back Rubber |
| Clean-Up II | Permethrin | Prevention – Fly Control* | Local | Short | None | EPA | 2ee, Florida, Alabama, Mississippi | Cattle, horses | Pour-on Wipe-On Spray |
| Cylence Pour-On Insecticide | Permethrin | Prevention – Fly Control* | Local | Short | None | EPA | 2ee, Florida, Alabama, Mississippi | Cattle | Pour-On |
| Tanidil | coumaphos, propoxur | Treatment & Prevention | Local | Short | Meat 28dys; Milk 28dys | EPA | Section 18 Emergency Use – Available only through APHIS. | Cattle, swine, goats, sheep, horses, other domestic ungulates, captive and temporarily captured wild and exotic ungulates and canids | Topical Powder |
Note: Veterinary extra-label drug use (ELDU) is a legally permitted practice where veterinarians use FDA-approved drugs in ways not listed on the label (different species, dose, indication, etc.), under strict conditions set by the Animal Medicinal Drug Use Clarification Act (AMDUCA).
EPA FIFRA Section 2(ee) Products are used as recommendations. It cannot specifically contradict the EPA labeling or restrictions. These 2(ee)s are specifically adding a target pest with no change of the label use of the product. 2(ee) approvals are state-specific.