New World Screwworm Products

New World Screwworm Approved Products

As of: February 10, 2026

The following information will be updated accordingly with new approvals from FDA and EPA. It is the intent of USAHA to provide up-to-date, accurate information. If you are aware of any updates needed, please submit those to brichey@usaha.org.

LIVESTOCK

Product Active Ingredient(s) Prevention Prophylaxis Treatment C&D Local / Systemic Duration Withhold Meat Milk Regulatory Agency Authorization Species Route of Administration
Dectomax CA1 Doramectin 1% All Systemic Long Meat 35 dys Not for Dairy Cattle over 20 Mo of age FDA Conditional Approval for NWS Cattle Injectable
Dectomax & Generics Doramectin 1% All Systemic Long Meat 35 dys Not for Dairy Cattle over 20 Mo of age FDA Approved (ELDU) Cattle Injectable
Ivomec & Generics Ivermectin 1% All Systemic Long Meat 35 dys Not for Dairy Cattle of breeding age Not for calves to be processed for veal FDA Approved (ELDU) Cattle, swine, reindeer, bison, fox Injectable
Exzolt Cattle-CA1 Lotilaner All Systemic Long For use in beef cattle 2 months of age and older and replacement dairy heifers less than 20 months of age. Not for use in bulls intended for breeding 1 year of age and older, dairy calves, and veal calves FDA Conditional Approval for NWS Cattle Pour-on
Catron IV Permethrin Prophylaxis Treatment Local Short None EPA Registered Cattle, sheep, goats, hogs, horses Spray
Co-Ral Fly & Tick Spray Coumaphos Prevention – Fly Control Local Long Meat 0 Milk 14 days EPA 2ee, Florida Cattle Spray Back Rubber
Elector PSP Spinosad C&D Premises Long N/A – Premise EPA 2ee, Texas Farm Animal Spray
Cylence Ultra Premise Beta-cyfluthrin C&D Premises Long N/A – Premise EPA 2ee, Texas Farm Animal Spray
Vapona Dichlorvos C&D Premises Long N/A – Premise EPA 2ee, Texas Farm Animal Spray / Fog
Permectrin Fly & Louse Dust Permethrin Prevention – Fly Control* Local Long None EPA 2ee, Florida Cattle, sheep, horses Dust
Permectrin CDS Permethrin Prevention – Fly Control* Local Long None EPA 2ee, Florida Cattle, sheep, horses Spray, Pour-On, Back Rubber
Clean-Up II Permethrin Prevention – Fly Control* Local Short None EPA 2ee, Florida Cattle, horses Pour-on Wipe-On Spray
Cylence Pour-On Insecticide Permethrin Prevention – Fly Control* Local Short None EPA 2ee, Florida Cattle Pour-On
F10 Antiseptic Wound Spray with Insecticide benzalkonium chloride, polyhexanide and cypermethrin topical solution Tx & Px Local?/?Systemic Shirt Meat 30dys – Milk 10dys FDA Emergency Use Authorization Cattle, Horses, Minor Species of Hoof Stock, Raptors, Wild Birds, Pet Birds, Captive Wild, Exotic, and Zoo Mammals Topical

Note: Veterinary extra-label drug use (ELDU) is a legally permitted practice where veterinarians use FDA-approved drugs in ways not listed on the label (different species, dose, indication, etc.), under strict conditions set by the Animal Medicinal Drug Use Clarification Act (AMDUCA).
EPA FIFRA Section 2(ee) Products are used as recommendations.  It cannot specifically contradict the EPA labeling or restrictions.  These 2(ee)s are specifically adding a target pest with no change of the label use of the product. 2(ee) approvals are state-specific.

COMPANION ANIMALS

Product Active Ingredient(s) Prevention / Prophylaxis / Treatment Local / Systemic Duration Withhold Meat / Milk Regulatory Agency Authorization Species Route of Administration
Capstar, Bestguard Nitenpyram All Systemic Short N/A FDA Approved (ELDU) Dogs, Cats Oral tablet
NexGard Afoxolaner All Systemic Long N/A FDA Approved (ELDU) Dogs Oral tablet
Simparica Simparica Trio Sarolaner All Systemic Long N/A FDA Approved (ELDU) Dogs Chewable tablet
Interceptor Milbemycin oxime All Systemic Long N/A FDA Approved (ELDU) Dogs, Cats Chewable tablet
Trifexis Milbemycin oxime and spinosad All Systemic Long N/A FDA Approved (ELDU) Dogs Chewable tablet
Comfortis Spinosad All Systemic Long N/A FDA Approved (ELDU) Dogs, Cats Chewable tablet
Credelio Dog and Credelio Cat Lotilaner All Systemic Long N/A FDA Emergency Use Authorization Dogs, Cats Chewable tablet
Credelio Quattro CA1 Lotilaner All Systemic Long N/A FDA Conditional Approval Dogs, Cats Chewable tablet
NexGard COMBO esafoxolaner, eprinomectin, and praziquantel topical solution All Topical Short N/A FDA Emergency Use Authorization Cats Topical
F10 Antiseptic Wound Spray with Insecticide benzalkonium chloride, polyhexanide and cypermethrin topical solution Tx & Px Local / Systemic Shirt N/A FDA Emergency Use Authorization Pet birds Topical

– Quick references –